About CHAI

The Clinton Health Access Initiative, Inc. (CHAI) is a global health organization committed to its mission of saving lives and improving health outcomes in low and middle-income countries by enabling governments and the private sector to strengthen and sustain quality health systems.

CHAI was founded in 2002 in response to the HIV/AIDS epidemic to dramatically reduce the price of life-saving drugs and increase access to these medicines in the countries with the highest burden of the disease. Over the following two decades, CHAI has expanded its focus. Today, along with HIV, we work in conjunction with our partners to prevent and treat infectious diseases such as COVID-19, malaria, tuberculosis, and hepatitis. Our work has also expanded into cancer, diabetes, hypertension, and other non-communicable diseases, and we work to accelerate the rollout of lifesaving vaccines, reduce maternal and child mortality, combat chronic malnutrition, and increase access to assistive technology. We are investing in horizontal approaches to strengthen health systems through programs in human resources for health, digital health, and health financing. With each new and innovative program, our strategy is grounded in maximizing sustainable impact at scale, ensuring that governments lead the solutions, that programs are designed to scale nationally, and that learnings are shared globally.

At CHAI, our people are our greatest asset, and none of this work would be possible without their talent, time, dedication, and passion for our mission and values. We are a highly diverse team of enthusiastic individuals across 40 countries with a broad range of skill sets and life experiences. CHAI is deeply grounded in the countries we work in, with the majority of our staff based in program countries. Learn more about our exciting work: http://www.clintonhealthaccess.org/

Background

Lenacapavir (LEN) is a long-acting injectable HIV prevention product that represents a potentially transformative opportunity for HIV prevention. Clinical trials have demonstrated near-complete protection against HIV acquisition, and its twice-yearly dosing schedule may substantially improve adherence compared to daily oral PrEP, particularly among key populations (KPs) facing stigma or structural barriers to care.

Despite its significant promise, investments supporting LEN introduction and evidence generation in Southeast Asia remain very limited. Without targeted investment in implementation research, LEN rollout in the region risks being delayed, limited in scale, and insufficient to inform broader adoption decisions by governments and donors.

CHAI proposes to conduct a Lenacapavir Implementation Research (LEN IR) study in Indonesia over a 2.5-year period (approximately 12 months of preparation and procurement, followed by 18 months of implementation research). The study will be conducted across approximately 20 sites in West Java and East Java provinces, targeting key populations including men who have sex with men (MSM), transgender women (TGW), people who inject drugs (PWID), and female sex workers (FSW). LEN will be delivered through two service delivery models: community/private clinics and KP-friendly public health centers (Puskesmas).

CHAI is seeking a qualified Indonesian university or academic institution to serve as a subrecipient, providing academic and technical rigor to the study design, ethical oversight, data collection, and dissemination of findings. It is noted that CHAI maintains ultimate responsibility for the program, including final decisions on study design, in coordination with the program donor.

Primary Research Questions

This study aims to answer the following primary research questions:

• Uptake: What proportion of eligible KPs initiate LEN (oral loading dose + first injection) during the enrollment period, across different service delivery models?
• Continuation: Among those who initiate LEN, what proportion receive an on-time continuation dose at 6 months and 12 months post-initiation?
• Feasibility & Acceptability: How feasible and acceptable is LEN delivery through community/private clinics and public health centers, from both client and provider perspectives?
• Cost: What are the full costs of delivering LEN across different service delivery models, including staff/HR time, demand generation, and commodity costs?
• Sustainability: Can LEN be integrated into existing service delivery infrastructure, and what financing mechanisms could support sustained provision beyond the grant period?

Scope of Work

The university subrecipient shall complete the following activities in close collaboration with the CHAI Indonesia team, which maintains dedicated program staff throughout the study period:

a. Study Design and Protocol Development

• Develop a comprehensive and rigorous implementation research protocol in collaboration with CHAI and the Ministry of Health
• Define appropriate sampling design and sample size requirements across implementation sites in West Java and East Java
• Design, pilot, and pre-test all data collection tools prior to implementation, including provider survey instruments and key informant interview guides

b. Regulatory Support — Special Access Scheme (SAS)

• Support CHAI in facilitating the SAS regulatory process through BPOM as the accelerated regulatory pathway for LEN importation and use in Indonesia
• Assist in the preparation, compilation, and submission of all required SAS documentation in accordance with BPOM requirements
• Liaise with relevant regulatory bodies and academic networks to expedite the SAS approval process
• Monitor the progress of SAS approval and coordinate with CHAI Indonesia to address any regulatory queries in a timely manner

c. Ethical Clearance

• Develop and submit the study protocol to the relevant IRB and/or CHAI Scientific and Ethics Review Committee (SERC)
• Obtain ethical clearance and all required administrative approvals prior to study commencement
• Respond to reviewer feedback and ensure the protocol is finalized and approved in a timely manner

d. Data Collection and Management

The university partner is expected to oversee and manage data collection activities, including supervising trained data collectors and ensuring data quality. Specific responsibilities include:

• Oversee quantitative data collection, including individual-level data from SI PrEP and/or SIHA
• Oversee the administration of provider surveys at all implementation sites, managing data collectors, reviewing data quality, and ensuring completeness and accuracy of survey responses
• Oversee the conduct of approximately 20 Key Informant Interviews (KIIs) across implementation sites. Key informant groups shall include MoH officials, PHO & DHO officials, healthcare workers, community organization representatives, and relevant stakeholders involved in HIV programming such as WHO, UNAIDS, etc.
• Perform responsible data management, maintaining data quality, security, and confidentiality throughout the data lifecycle

e. Data Analysis and Synthesis

• Analyze and synthesize quantitative and qualitative data to produce key findings aligned with primary research questions
• Conduct cost analysis to estimate the full unit cost of LEN delivery across service delivery models
• Assess the feasibility of self-financing or co-financing models as part of the sustainability analysis

f. Reporting and Dissemination

• Produce a comprehensive final research report in both Bahasa Indonesia and English, with compelling data visualizations, lessons learned, and actionable recommendations
• Develop a 5-page policy brief summarizing key findings for government and donor audiences
• Prepare and submit at least one peer-reviewed publication based on study findings
• Present findings at national and/or international HIV/health conferences

g. Coordination and Collaboration

• Facilitate regular coordination meetings with CHAI, the Ministry of Health, and other key stakeholders throughout the study period
• Conduct project implementation and financial management in compliance with CHAI’s SOPs, guidelines, and sub-recipient agreements
• Collaborate closely with the CHAI Indonesia team on all research-related activities, ensuring alignment with program objectives and timelines

Qualifications

CHAI invites qualified universities or academic institutions with teams of experts and health researchers to participate in this project.

Required Qualifications

Institutional:

• Accredited Indonesian university or academic institution that either (a) has an active and recognized IRB/ethics committee, or (b) demonstrates a track record of successfully obtaining ethical clearance through a recognized external IRB in Indonesia
• Demonstrated experience in conducting health-related implementation research or operational research in Indonesia
• Established working relationships with the Ministry of Health and/or sub-national health authorities

Team:

• Principal Investigator (PI): Doctoral degree (Ph.D. or MD equivalent) in public health, epidemiology, infectious diseases, or a related field, with a proven track record in HIV-related research
• At least one (1) additional team member with an advanced degree in public health or relevant disciplines, with experience in mixed-methods research design and implementation
• Comprehensive knowledge of the Indonesian health system, HIV program architecture, and PrEP service delivery
• Excellent written and oral communication skills in both Bahasa Indonesia and English for all key team members

Proposed minimum team structure: one (1) Principal Investigator + one to two (1–2) Field Coordinators or Data Collectors with experience working with key populations.

Preferred Qualifications

• Prior experience in the introduction or implementation research of PrEP products (oral or injectable) in Indonesia or similar settings — considered a significant added advantage
• Experience managing large-scale, multi-site studies with diverse key population groups
• Familiarity with SI PrEP, SIHA, or other national health information systems
• Situational knowledge of West Java and/or East Java provinces and their key population communities

Project Timeline & Key Deliverables

The total expected duration of the assignment is approximately 2.5 years, aligned with the overall LEN IR program timeline in Indonesia.

Budget & Duration

IDR 700.000.000

Maximum total budget for the full 2.5-year program period, inclusive of all applicable taxes.

This ceiling covers honoraria (in accordance with the applicable SBU regulation from the Ministry of Finance), travel and transportation, and other direct operational costs. The following cost components will be covered directly by CHAI Indonesia and fall outside the subrecipient budget ceiling: meeting and workshop organization; HCW and CSO training activities; monitoring and evaluation; LEN commodity importation and regulatory costs; Special Access Scheme (SAS) fees; and IRB submission fees.

Budget proposals must be submitted in Excel format with a full cost breakdown by year, including unit costs, quantities, and total amounts per budget line. All honoraria rates must comply with the applicable SBU regulation.

Application Requirements

Interested applicants must submit a proposal of no longer than five (5) pages (excluding annexes) in English, including the proposed project timeline. The proposal shall include:

1. Research title
2. Institutional background and team qualifications
3. A brief statement (maximum half a page) on the applicant’s understanding of the LEN IR program objectives and how the institution’s expertise uniquely positions it to contribute to this study
4. A proposed methodological approach (2–3 pages), acknowledging that the final detailed methodology will be developed collaboratively with CHAI following contract signing
5. A proposed implementation plan specifying the university partner’s contributions and team structure, noting that the plan should complement and integrate with CHAI’s dedicated program resources rather than function as a standalone operation
6. Anticipated risks and mitigation strategies
7. Reference list / bibliography
8. Annex 1: Annotated budget in Excel format with full breakdown by year (honoraria in accordance with SBU regulation, activities, travel, and other anticipated costs)
9. Annex 2: CVs of key personnel in a single merged PDF file
10. Annex 3: At least one (1) sample of previous work (published paper, project portfolio, or final report in PDF format)

All proposals will be evaluated based on five criteria: proposal quality (clarity and rigor); proposed methodological approach; relevance to LEN IR objectives; team qualifications and institutional capacity; and budget rationale.

How to Apply

• Submission Deadline: 24 July 2026
• Please submit your complete application package electronically to: Email: indonesiaoffice@clintonhealthaccess.org ; CC: franto@clintonhealthaccess.org
• Subject line: “LEN IR Indonesia – Subrecipient Proposal_[University Name]”

Ensure that each file submitted is clearly labelled with the institution name (e.g., Narrative Proposal_[Institution Name]). Only shortlisted candidates will be notified. Late or incomplete applications will not be considered.